Wine is a free and open source utility that allows you to run certain Windows applications on non-Windows operating systems including Linux and Android, macOS. And starting with Wine version 6.0.1, this also includes support for running 64-bit Windows applications on Macs with Apple M1 processors.
Apple Silicon support is courtesy of code contributions from the folks at CodeWeavers, the makers of Crossover, which is essentially a bloated version of Wine with commercial support. CodeWeavers has been working to enable Apple Silicon support in its software since last year, and now some of that code has been integrated upstream from Wine.
A few things to keep in mind about Wine is that it is a Windows Compatibility Layer and not an emulator or virtual machine. Some Windows applications may not work at all and some hardware may not be supported. Mac users can find some of the capabilities and limitations in a macOS FAQ on the WineHQ website.
But with Wine64 support on Macs with Apple M1 processors, you will at least be able to install and run some Windows-supported games and applications from Wine on Apple’s latest laptops and desktops.
Other changes in Wine 6.0.1 include translation and documentation updates as well as bug fixes for some games and applications, including several Adobe applications, The witcher 3, Batman: Arkham Origins, and The sims 3.